Title: Biomonitoring and dietary intake of pesticide exposure: An insight over different sex and socio-economic observation on children

Abstract

The biomonitoring of urine dialkyl phosphate metabolites was used to determine the level of pesticide exposure in children exposed to organophosphorus pesticides. There are very limited studies evaluating pesticide exposure in teenagers of either sex. The major goal was to create a modelling strategy for determining metabolite concentrations that were based on a combination of exposure and dosage. As an additional goal, we were trying to see whether pesticide exposure among teenagers of various genders had changed significantly. In order to maintain children's urine metabolites levels below specified values, we used a coupled exposure-dose modelling technique to calculate the concentrations of metabolites that would keep children's urine metabolites levels below a certain threshold. We collected urine samples from 377 children ages 6–10 and 11–15 from Hyderabad, India, including 188 males and 189 girls. First-morning first urine samples (3.05 µmol L-1) were closely linked with the same-day 24-hr samples (1.7 µmol L-1) with 99.4 percent accuracy (r = 0.997, model R2 ≈ 0.994, p < 0.00), according to the findings. Girls had an 87.5 % detection rate of DAP metabolites, compared to a 74% detection rate for DAP metabolites among boys, regardless of the quantity of traditional food consumed. Pesticide metabolite levels were significantly greater in the female group (87% higher) than in the male group.